Power Calculations for Each Hypothesis

Posted on January 20, 2009

Guillermo J. Prado (bio) explains why a broad statement about power is not sufficient for a grant proposal.


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I don't see how a research application can be funded if you don't have sample size determinations and power calculations in your application. And when I review grants, not only do you have to have a broad statement about power and sample size calculations, but I think you have to have power and sample size for each research hypothesis.

So some research hypotheses may involve a binary outcome while others may involve a continuous outcome, for example. And power for those two hypotheses will not be the same. So generally for binary data, you have a lot less power, so you would need a lot more participants than you would for a continuous variable. So in writing research grant applications, you really do have to have power statements for each research hypothesis.

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Excerpted from an interview with researcher at the 2008 National Hispanic Science Network on Drug Abuse Conference in Bethesda, MD.

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